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Premium Herbal Ingredients and Clinical Studies

Green Coffee Bean Extract
1.”Significant reductions were observed in body weight (−8.04 ± 2.31 kg), body mass index (−2.92 ± 0.85 kg/m2), and percent body fat (−4.44% ± 2.00%), as well as a small decrease in heart rate (−2.56 ± 2.85 beats per minute), but with no significant changes to diet over the course of the study. Importantly, the decreases occurred when subjects were taking GCA. The results are consistent with human and animal studies and a meta-analysis of the efficacy of green coffee extract in weight loss. The results suggest that GCA may be an effective nutraceutical in reducing weight in preobese adults, and may be an inexpensive means of preventing obesity in overweight adults.
Reference: Diabetes Metabolic Syndrome and Obesity
Link: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267522/

2.”In a double-blind, placebo-controlled clinical trial, 50 volunteers used green coffee bean extract for 60 days. Each participant took either the green coffee bean extract or a placebo twice a day with their main meals. At the end of the study, participants using the extract lost 5.7% of their initial weight, corresponding to an average weight loss of 5 kg or 11 lbs. versus a 2.9% weight loss (2.45 kg or 5.4 lbs.) in the placebo group. That’s basically twice the effect in just 2 months using the extract!”
Reference: Europharmceuticals USA
Link: http://www.europharmausa.com/DBFiles/Greensheet/296.pdf

3.”The show’s Medical Unit enlisted 100 women between the ages of 35 and 49 who were overweight with BMIs between 25 and 45. The women were not pregnant or breastfeeding and didn’t have any major medical problems including diabetes, or history of heart attack or stroke. These women received either the green coffee bean extract or a placebo, and were instructed to take 400mg capsules, three times a day – 30 minutes before each meal. No participant knew which pill they were given. Furthermore, the participants were instructed to not change their diet, and to keep a food journal that would help The Dr. Oz Show learn what these women were eating. After two weeks, the study participants were weighed.In two weeks, the group of women who took the green coffee bean extract lost, on average, two pounds. However, the group of women who took the placebo lost an average of one pound – possibly because they were more aware of their diet for that two weeks because of the required food journal.”
Reference: Dr. Oz Show
Link: http://www.doctoroz.com/videos/green-coffee-bean-project

 

Green Tea Extract
1.”Clinical studies suggest that green tea extract may boost metabolism and help burn fat. One study found that the combination of green tea and caffeine improved weight loss and maintenance in people who were overweight and moderately obese. Some researchers think that substances in green tea known as catechins are responsible for the herb’s fat-burning effect.”
Reference: University of Maryland Medical Center

Link: http://www.umm.edu/altmed/articles/green-tea-000255.htm

2.”A reduction of body weight ( – 1·29 (sem 0·35) kg) and fat mass (0·82 (sem 0·27) kg) in the experimental group was found after 6 weeks, and no adverse effects were observed. After refraining from consumption for 2 weeks, sustained effects on body weight and fat mass were observed. We conclude that continuous intake of catechin-rich green tea in combination with inulin for at least 3 weeks may be beneficial for weight management.”
Reference: Department of Nutrition, I-Shou University
Link: http://www.ncbi.nlm.nih.gov/pubmed/22032343

3.”There was a statistically significant weight loss only in GTG [71.5±12.6 kg to 70.3±12.6 kg (p<0.001)]. A statistically significant decrease in BMI [-0.5±0.4 kg/m2 in GTG and -0.2±0.6 kg/m2 in CG (P=0.032)] and waist circumference [-2.2±2.0 cm in GTG and – 0.3±1.8 cm in CG (P=0.002)] were observed. The consumption of green tea was effective in inducing weight loss, reducing BMI and waist circumference in the elderly with MS.”
Reference: US National Library of Medicine: National Institutes of Health
Link: http://www.ncbi.nlm.nih.gov/pubmed/23131813

 

Apple Cider Vinegar
1.”A 2009 study by the Mizkan Group conducted on 175 participants of comparable body types, showed noteworthy decreases in waistline, body mass indexing, visceral fat and an increase in overall energy levels. The study used 0 mL, 15 mL and 30 mL daily doses of vinegar mixed with a beverage for 12 weeks. Subjects that consumed the 30 mL dose daily showed the most significant weight loss results. “
Reference: Livestrong.com
Link: http://www.livestrong.com/article/293098-apple-cider-vinegar-with-water-for-weight-loss/

2.”In a 2004 study in “Diabetes Care,” insulin-resistant individuals who drank vinegar and water followed by a meal enjoyed significantly improved insulin sensitivity compared to a control group. The study authors concluded that vinegar’s effects may be similar to those of some popular diabetes drugs. Of course given the connection between insulin levels and fat storage, these results support vinegar’s use as a fat burning food.Learn more: http://www.naturalnews.com/033745_apple_cider_vinegar_weight_loss.html#ixzz2LhfIrAyT “
Reference: Diabetes Care Journal
Link: http://www.naturalnews.com/033745_apple_cider_vinegar_weight_loss.html

3.”A study geared at testing vinegar’s long-term effects also found that taking vinegar yielded moderate weight loss. In the four-week study, half of participants took a two-tablespoon dose of vinegar prior to each of two meals daily, while the other half were told to avoid vinegar. Participants taking the vinegar lost an average of two pounds over the four-week period, while weight remained constant in the non-vinegar group. And some participants taking vinegar lost up to four pounds. “
Reference: Arizona State University
Link: http://www.sciencenews.org/view/generic/id/5732/description/Vinegar_as_a_Sweet_Solution

 

Grapefruit Herb Powder
1.”The grapefruit diet is apparently not a myth. That’s what a new study by the Nutrition and Metabolic Research Center at Scripps Clinic has confirmed. Researchers there found that the simple act of adding grapefruit and grapefruit juice to one’s diet can result in weight loss.The 12-week pilot study, led by Dr. Ken Fujioka, monitored weight and metabolic factors, such as insulin secretion, of the 100 men and women who participated in the Scripps Clinic ‘Grapefruit Diet’ study.On average, participants who ate half a grapefruit with each meal lost 3.6 pounds, while those who drank a serving of grapefruit juice three times a day lost 3.3 pounds. However, many patients in the study lost more than 10 pounds. “
Reference: Dr. Ken Fujioka
Link: http://www.medicalnewstoday.com/releases/5495.php

2.”After 12 weeks, the fresh grapefruit group had lost 1.6 kg, the grapefruit juice group had lost 1.5 kg, the grapefruit capsule group had lost 1.1 kg, and the placebo group had lost 0.3 kg. The fresh grapefruit group lost significantly more weight than the placebo group (P < .05). A secondary analysis of those with the metabolic syndrome in the four treatment groups demonstrated a significantly greater weight loss in the grapefruit, grapefruit capsule, and grapefruit juice groups compared with placebo (P < .02). There was also a significant reduction in 2-hour post-glucose insulin level in the grapefruit group compared with placebo. Half of a fresh grapefruit eaten before meals was associated with significant weight loss. In metabolic syndrome patients the effect was also seen with grapefruit products. Insulin resistance was improved with fresh grapefruit. Although the mechanism of this weight loss is unknown it would appear reasonable to include grapefruit in a weight reduction diet. “
Reference: Department of Nutrition and Metabolic Research
Link: http://www.ncbi.nlm.nih.gov/pubmed/16579728

3.”Participants who ate grapefruit lost an average of 3.6 lbs., persons who drank grapefruit lost an average of 3.3. lbs. and persons who took a placebo lost an average of 0.5 lb., according to “Journal of Medicinal Food” in spring 2006. Grapefruit helped participants lose about 1/3 lb. a week without otherwise changing their eating habits.”

Reference: Journal of Medicinal Food
Link: http://www.livestrong.com/article/511844-grapefruit-extract-weight-loss-products/

 

Caffeine
1.”High caffeine intake was associated with weight loss through thermogenesis and fat oxidation and with suppressed leptin in women. High caffeine consumers reduced weight, fat mass, and waist circumference more than low caffeine consumers; resting energy expenditure was reduced less and respiratory quotient was reduced more during weight loss (p < 0.01). “
Reference: Department of Human Biology, Maastricht University
Link: http://www.ncbi.nlm.nih.gov/pubmed/16076989

2.”In this 6-month placebo-controlled trial, herbal ephedra/caffeine (90/192 mg/day) promoted body weight and body fat reduction and improved blood lipids without significant adverse events. By last observation carried forward analysis, herbal vs placebo treatment decreased body weight (-5.3+/-5.0 vs. -2.6+/-3.2 kg, P<0.001), body fat (-4.3+/-3.3 vs. -2.7+/-2.8 kg, P=0.020) and LDL-cholesterol (-8+/-20 vs. 0+/-17 mg/dl, P=0.013), and increased HDL-cholesterol (+2.7+/-5.7 vs. -0.3+/-6.7 mg/dl, P=0.004).”
Reference: New York Obesity Research Center

Link: http://www.ncbi.nlm.nih.gov/pubmed/12032741

 

Acai Berry
1.”Compared to baseline, there were reductions in fasting glucose and insulin levels following the 30 day treatment (both p < 0.02). There was also a reduction in total cholesterol (p = 0.03), as well as borderline significant reductions in LDL-cholesterol and the ratio of total cholesterol to HDL-cholesterol (both p = 0.051). Compared to baseline, treatment with açai ameliorated the post-prandial increase in plasma glucose following the standardized meal, measured as the area under the curve (p = 0.047). There was no effect on blood pressure, hs-CRP or eNO.”
Reference: Medicus Research LLC
Link: http://www.ncbi.nlm.nih.gov/pubmed/21569436

2.”The Memorial Sloan-Kettering Cancer Center has found that acai berry has anti-inflammatory, antioxidant and apoptotic effects. It adds, however, that acai has not been proven to be effective for cancer in humans.”
Reference: Memorial Sloan-Kettering Cancer Center
Link: http://www.livestrong.com/article/228643-acai-berry-mangosteen/#ixzz2LhSL5art

 

Kelp
1.” If you are deficient in iodine and producing insufficient thyroid hormones to regulate your metabolism, then taking sea kelp products will increase your hormone production and hence your metabolic rate. This will automatically lead to weight loss even if you change nothing else in your life.Kelp contains many of the vitamins and minerals that can be deficient in a modern diet. If you have low levels of any of these then taking kelp may restore normal levels improving your digestion and normalizing your fluid balance. This may also make you lose weight.”

Reference: www.livestrong.com
Link: http://www.livestrong.com/article/292970-sea-kelp-weight-loss/
2.”Most notably, kelp is a rich, natural source of iodine which can provide adequate levels to stimulate a sluggish thyroid and encourage a healthy metabolism. A well operating metabolism is key for maintaining ideal body weight. Your metabolism, which is regulated by your thyroid gland, is the part of your body responsible for the way you use energy and burn calories; and iodine is the catalyst that jump starts the metabolic processes.
Reference: Global Healing Center Inc
Link: http://www.globalhealingcenter.com/natural-health/weight-loss-benefits-kelp/

 

Resveratrol
1.”Higher levels of body fat are associated with increased risk for development of numerous adverse health conditions. Phytochemicals are potential agents to inhibit differentiation of preadipocytes, stimulate lipolysis, and induce apoptosis of existing adipocytes, thereby reducing adipose tissue mass. Resveratrol decreased adipogenesis and viability in maturing preadipocytes; these effects were mediated not only through down-regulating adipocyte specific transcription factors and enzymes but also by genes that modulate mitochondrial function. Additionally, resveratrol increased lipolysis and reduced lipogenesis in mature adipocytes. In addition, combining resveratrol with other natural products produced synergistic activities from actions on multiple molecular targets in the adipocyte life cycle.”
Reference: University of Georgia
Link: http://www.ncbi.nlm.nih.gov/pubmed/21261640

 

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